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The hazard rate of genes for glioma patients with IDH1mt.
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The hazard rate of genes for glioma patients with IDH1mt.
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The hazard rate of genes for glioma patients with IDH1mt.
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Image Search Results


The hazard rate of genes for glioma patients with IDH1mt.

Journal: Frontiers in Immunology

Article Title: A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy

doi: 10.3389/fimmu.2022.1001381

Figure Lengend Snippet: The hazard rate of genes for glioma patients with IDH1mt.

Article Snippet: Primary antibodies used were as follows: HLA-DQA2 (1:200; Cat No. 42-669, ProSci, Fort Collins, CO, USA), HOXA3 (1:100; Cat No.ab230879, Abcam, Cambridge, UK), SAA2 (1:500; Cat No. CAU25292; Biomatik, Kitchener, Canada), CD8 (1:4000; Cat No. 66868-1-Ig; Proteintech, Wuhan, China), and CD86 (1:250; Cat No. ab220188, Abcam).

Techniques:

Hub genes selected to construct the risk model. (A, B) LASSO analysis for hub genes associated with the survival rate of IDH1mt-glioma patients. (C) Multivariate Cox regression analysis of HLA-DQA2 , HOXA3 , and SAA2. These three genes were used to construct the risk model.

Journal: Frontiers in Immunology

Article Title: A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy

doi: 10.3389/fimmu.2022.1001381

Figure Lengend Snippet: Hub genes selected to construct the risk model. (A, B) LASSO analysis for hub genes associated with the survival rate of IDH1mt-glioma patients. (C) Multivariate Cox regression analysis of HLA-DQA2 , HOXA3 , and SAA2. These three genes were used to construct the risk model.

Article Snippet: Primary antibodies used were as follows: HLA-DQA2 (1:200; Cat No. 42-669, ProSci, Fort Collins, CO, USA), HOXA3 (1:100; Cat No.ab230879, Abcam, Cambridge, UK), SAA2 (1:500; Cat No. CAU25292; Biomatik, Kitchener, Canada), CD8 (1:4000; Cat No. 66868-1-Ig; Proteintech, Wuhan, China), and CD86 (1:250; Cat No. ab220188, Abcam).

Techniques: Construct

Expression of HLA-DQA2 , HOXA3 , SAA2 , CD86 , and CD8 in IDH1mt-glioma tissues. IDH1mt-glioma tissues were divided into long- and short-term survival groups according to the patient’s number of days of survival with the cut-off as 15 months. (A) The IHC score of HLA-DQA2 , HOXA3 , and SAA2 in IDH1mt-glioma tissues in long- and short-term groups. (B) Representative figures of expression of HLA-DQA2 , HOXA3 , and SAA2 in long- and short-term group IDH1mt-glioma tissues. (C) Expression of CD86 and CD8 in long- and short-term group IDH1mt-glioma tissues. (D–F) The diagnostic value of HLA-DQA2 , HOXA3 , and SAA2 for distinguishing long- and short-term survival of IDH1mt-glioma patients. ** P < 0.01.

Journal: Frontiers in Immunology

Article Title: A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy

doi: 10.3389/fimmu.2022.1001381

Figure Lengend Snippet: Expression of HLA-DQA2 , HOXA3 , SAA2 , CD86 , and CD8 in IDH1mt-glioma tissues. IDH1mt-glioma tissues were divided into long- and short-term survival groups according to the patient’s number of days of survival with the cut-off as 15 months. (A) The IHC score of HLA-DQA2 , HOXA3 , and SAA2 in IDH1mt-glioma tissues in long- and short-term groups. (B) Representative figures of expression of HLA-DQA2 , HOXA3 , and SAA2 in long- and short-term group IDH1mt-glioma tissues. (C) Expression of CD86 and CD8 in long- and short-term group IDH1mt-glioma tissues. (D–F) The diagnostic value of HLA-DQA2 , HOXA3 , and SAA2 for distinguishing long- and short-term survival of IDH1mt-glioma patients. ** P < 0.01.

Article Snippet: Primary antibodies used were as follows: HLA-DQA2 (1:200; Cat No. 42-669, ProSci, Fort Collins, CO, USA), HOXA3 (1:100; Cat No.ab230879, Abcam, Cambridge, UK), SAA2 (1:500; Cat No. CAU25292; Biomatik, Kitchener, Canada), CD8 (1:4000; Cat No. 66868-1-Ig; Proteintech, Wuhan, China), and CD86 (1:250; Cat No. ab220188, Abcam).

Techniques: Expressing, Diagnostic Assay